Advanced Science Journal

สารจากบรรณาธิการ/สารบัญ

Editor — 2024-01-02

วารสารก้าวทันโลกวิทยาศาสตร์ (Advanced Science Journal) เป็นวารสารของคณะวิทยาศาสตร์และเทคโนโลยี มหาวิทยาลัยราชภัฏบ้านสมเด็จเจ้าพระยา ได้เปิดรับบทความวิชาการและบทความวิจัยตีพิมพ์เผยแพร่มาอย่างต่อเนื่องเป็นปีที่ 24 โดยผ่านการรับรองคุณภาพจากศูนย์ดัชนีการอ้างอิงวารสารไทย หรือ TCI (จนถึง 31 ธันวาคม 2567) และอยู่ในฐานข้อมูล TCI กลุ่มที่ 2 (ผลประเมินคุณภาพวารสารวิชาการที่อยู่ในฐานข้อมูล TCI รอบที่ 4 พ.ศ. 2563 – 2567)

ฉบับนี้เป็นปีที่ 24 ฉบับที่ 1 ประจำเดือนมกราคม – มิถุนายน 2567 เพื่อรวบรวมเผยแพร่ผลงานวิจัยและผลงานวิชาการ ของบุคลากรทั้งภายในและภายนอกมหาวิทยาลัย ในฉบับนี้มีบทความวิจัย 11 เรื่อง และบทความวิชาการ 1 เรื่อง ที่มีเนื้อหาทางวิชาการที่หลากหลายและครอบคลุมศาสตร์หลายด้านทางวิทยาศาสตร์ วิทยาศาสตร์ประยุกต์ วิทยาศาสตร์สุขภาพ และเทคโนโลยี ที่สามารถนำไปประยุกต์ใช้กับศาสตร์ที่เกี่ยวข้องได้

ในนามของกองบรรณาธิการใคร่ขอขอบพระคุณผู้นิพนธ์ทุกท่านที่ได้ให้ความสนใจส่งผลงานตีพิมพ์เผยแพร่ในวารสารก้าวทันโลกวิทยาศาสตร์ ขอขอบพระคุณผู้ทรงคุณวุฒิที่ประเมินคุณภาพบทความ และขอขอบคุณกองบรรณาธิการทุกท่านที่ร่วมดำเนินการและพัฒนาคุณภาพวารสารก้าวทันโลกวิทยาศาสตร์มาโดยตลอด และหวังเป็นอย่างยิ่งว่าวารสารฉบับนี้จะเป็นประโยชน์ต่อนักวิจัย นักวิชาการ และผู้ที่สนใจทุกท่าน สุดท้ายนี้ขอเชิญชวนผู้สนใจทุกท่านส่งผลงานตีพิมพ์เผยแพร่บทความวิชาการและบทความวิจัยลงวารสาร ท่านสามารถศึกษารายละเอียดได้จากเว็บไซต์ https://li02.tci-thaijo.org/index.php/adscij หรือ http://sci.bsru.ac.th/advscij/

Turning Knife Sharpener with Automatic Electric Control System

yossawat Cheewaworanontree — 2024-01-02

This article aims to design and create an automatic electrical control system for a secret folding knife set. Since folding knives are tools used to cut and shape workpieces according to desired patterns, the act of folding the blade is currently done manually by gripping the folding knife and using a sharpening machine. This process requires skill, as an unskilled approach can lead to incorrect angles and dimensions of the folding knife, resulting in imprecision and potential danger. Therefore, designing and building an automatic electrical control system for a secret folding knife set involves principles and theories related to the field of knife making, such as automatic electrical system control, types of folding machines, folding knife blades, blade sharpening techniques, design principles, and the fundamentals of machine design. This approach aims to apply these principles to create an efficient and effective secret folding knife set that reduces work time, provides convenience, speed, and safety in usage. Additionally, it eliminates the need for manual folding by a person, instead utilizing an assembled folding knife set. After assembling, the secret folding knife set will automatically perform the folding process, resulting in a finely finished work surface and accurate blade angles as per specified dimensions.

Development of Application for Cultural Tourism Promotion in Thonburi area with Augmented Reality Technology

Direk Akkahad — 2024-01-02

The objectives of this research were to 1) develop an application to promote cultural tourism in the Thonburi area with augmented reality technology and 2) evaluate the effectiveness of the application to promote cultural tourism in the Thonburi area with augmented reality technology. The sample group used in this research is Tourists who come to visit the area on the Thonburi area. There were 76 Thai tourists and 38 foreign tourists, totaling 114 people. The research tools consisted of 1) an application to promote tourism 2) an evaluation form for application efficiency. Data were analyzed using percentage, mean and standard deviation. The results of the research were as follows 1) the results of developing an application to promote cultural tourism in the Thonburi area; The application contains information that is a video introduction of 19 tourist attractions, 3D models and AR codes prepared in the form of a travel guide. When you open the app and look at an AR code image, a 3D model will appear superimposed on the image. Can be rotated and enlarged 2) The performance evaluation of the application found that users were satisfied with the overall performance of the application is at a high level (= 3.88, S.D. = 0.92). When considering each aspect, it was found that users were satisfied at a high level in all aspects. In descending order as follows: benefits of the application to use (= 4.02, S.D. = 0.95), design and formatting (= 3.87, S.D. = 0.90), and Content (= 3.74, S.D. = 0.88)

Development of Walking Electric Lawn Mower for Ramphan Community, Tha Mai District Chanthaburi Province

Kritsana chantasit — 2024-01-02

This research aimed to develop a walking electric mower for the Ramphan community, Tha Mai district, Chanthaburi province. This machine was used to eliminate some weed in the gardens, decrease the fuel cost when compare to the traditional mower, reduce the pollution and it is environmentally friendly. The size of mover body was 40, 120 and 100 cm. The range between ground to mover body was 6 cm. Two wheels size of 6.5 inch was used to move by pushing. The total mower weight was 18 kg. The mower was conducted with 24 V and 20 Ah of lithium-ion phosphate battery that use as the power supply for the DC electric motor type 24 V and 350 W. The DC electric motor was used to supply power to the mower blade with a speed of 2,750 rpm. The working time of mover was 2 h per a battery charging while the time for charging the battery was 4 h. From the mower test by cutting grass for the area 1 job or 400 cm², the result show that the electric mower and fuel mower took the similar time period to cut grass around 2 h. The electrical cost and fuel cost were 4.11 and 41.89 Baht (0.8 L), respectively. The payback period of the mower was 0.54 year.

Benjakul Water Extract Affects Liver Cell Aging in Obese Mice with High-fat Diet

Kevalin Vongthoung — 2024-01-02

The Benjakul water extract (BWE) is a traditional remedy in Thailand utilized for managing blood sugar levels. However, there has been limited research into the effects and mechanisms of BWE on the liver. This study aimed to evaluate the anti-aging properties of BWE by assessing the activity of the Senescence-associated beta-galactosidase (SA-β-gal) enzyme in the liver cells of obese mice subjected to a high-fat diet. The study involved 16 male Sprague-Dawley rats, divided into 6 groups of 3 rats each. Following a 4-week period of high-fat diet consumption, the rats' body weight, blood sugar levels, and SA-β-gal immunohistochemistry in the liver were evaluated. Comparing the results with the control group (rats on a normal diet), all rat groups exhibited increased body weight, blood sugar levels, and SA-β-gal staining in the liver, indicating statistical significance. Among the groups fed a high-fat diet, those supplemented with low-dose BWE and high-dose BWE showed reduced SA-β-gal staining. In contrast, the group receiving a high-fat diet along with wild betal leaf bush water extract, and the group receiving a high-fat diet along with Metformin, exhibited increased SA-β-gal staining. Moreover, wild betal leaf bush water extract and Metformin were found to accelerate cellular aging in the liver cells of obese rats receiving a high-fat diet. Conclusion, both low and high doses of BWE demonstrated potential in mitigating liver cell aging in obese rats subjected to a high-fat diet. Furthermore, wild betal leaf bush water extract and Metformin were observed to expedite liver cell aging, suggesting that BWE might possess protective properties against the aging process in liver cells under conditions associated with high levels of dietary fat.

Kinetic Study of Plasmodium falciparum Orotate Phosphoribosyl Transferase in the Presence of Activator and Inhibitor

Patsarawadee Paojinda — 2024-01-02

Objective: To find the chemicals which have the stimulating or inhibitory properties on orotate phosphoribosyl transferase enzymes (OPRT) of Plasmodium falciparum. Method: construction of PfOPRT gene was ligated in pQE 30Xa plasmid and transfer into E. coli M15 and prove the construct recombinant plasmid. After it was proved to be the desired gene, the enzyme was expressed and purified. The performance was tested and metal ions were tested for activation and Orotidine 5'-Monophosphate (OMP) reaction products for inhibition. Result: The effective cofactor of OPRT is Mg^{2 +}with V_max = 64.25 µmol/min and K_m = 58.82 µM and the enzyme activity without a cofactor is equal to zero. The cofactor was converted to Zn^{2 +}, the OPRT activity was reduced was show V_max = 9.35 µmol/min and K_m= 136.24 µM. A reverse inhibition test was performed using the product obtained from the reaction OMP, resulting in a competitive inhibition of OPRT.

The Effects of Captan Solution and Bioextract Affecting on Fungal Prevention the Growth of Caladium bicolor Vent.

Ratima Sahawisit — 2024-01-02

The objectives of this research: 1) to compare the captan solution and biofertilizer on the antifungal effect of Caladium bicolor Vent 2) to optimum ratio of biofertilizer for bonbon growth. A 28-day study of captan solution and bio-fermentation solution on prevention of fungal infection of Caladium bicolor Vent. tubers showed that the best formula was the biofermentation of mangosteen peel with neem at a ratio of 75:25%, where the percentage of survival and anti-fungal infection was 75 percent, and causes the highest growth of bonsai. It was found that the highest mean height was 9.42±4.83 cm with the highest average number of leaves 3.00±1.75 leaves.

ALOHA Sharing with Google Earth Simulation and the Impacts of LPG Tank Truck Leakage Accident Based on the Transportation at Bangna-Trad Road Km.19 Samut Prakan Province

Kitja Chitpirom — 2024-01-02

Liquefied petroleum gas (LPG) is now shipped using a truck and it is found to have an accident causing a leak or explosion affecting life, property, and the environment. The purpose of this research is to simulate the situation and assess the impacts of an LPG tank truck leakage accident based on the transportation at Bangna-Trad Road Km.19, Samut Prakan Province by using ALOHA sharing with Google Earth software. It is a geographic representation of information on electronic maps by simulating the climate according to the 3 seasons of Thailand; summer, rainy and winter seasons, in order to analyze the radius and direction of chemical distribution, the degree of severity of impact on communities and surrounding accident areas, and compare the hazard effects of each season.

The result is that, there are good scenarios of the spread of liquid petroleum gas in various situations. The result is found that the difference in in temperature, humidity, wind speed and wind direction in each season can lead to different hazards. The data of this model can be used to improve an emergency response plan in the event of an incident in the area or as a lesson to further manage chemical leakage in other areas. However, the ALOHA program can only be used to predict chemical spills in open areas.

Antioxidant and Tyrosinase Inhibition Activities from Ethanolic Extracts of Mimusops elengi and Hibiscus sabdariffa Flowers and Dillenia indica and Abelmoschus esculentus Fruits

Nadaphast Koomklang — 2024-01-02

This research aims to study the bioactive compounds of extracts from Mimusops elengi, Hibiscus sabdariffa, Dillenia indica and Abelmoschus esculentus, which are indigenous to the Mon community in Phra Nakhon Si Ayutthaya province. The extracts were prepared using ethanol at concentrations of 0, 50, and 100% (v/v). After that, the extracts from four plants were analyzed for total phenolic content, free radical scavenging activity via DPPH and ABTS assays, and the inhibition of the enzyme tyrosinase. The results of the experiments showed that the extract from M. elengi at a concentration of 50% (v/v) had the highest total phenolic content, with a value of 141.63±0.71 milligrams per gram of dry sample. Additionally, the extract from this flower exhibited the best free radical scavenging activity with IC₅₀ values of 0.25±0.03 and 1.34±0.01 milligrams per milliliter for DPPH and ABTS assays, respectively. Furthermore, it showed the highest inhibition of tyrosinase enzyme activity at 60.87±3.27%. Therefore, the extracts from these flowers have potential for the development of natural herbal products that can promote local knowledge and benefit the community in the future.

The Effectiveness of Herbal Knee Braces to Relieve Knee Pain for the Elderly in Samrong Subdistrict, Phra Pradaeng District, Samut Prakan Province

Kanokwan Chotichai — 2024-01-02

This quasi–experimental research, Randomized Pretest-Posttest Control Group Design, aims to compare the pain before and after using the herbal knee brace, and to study the satisfaction after using the herbal knee brace in which the research study group consisted of 30 experiment and 30 comparison group. The tools used questionnaires to collect the data were the sociodemographic data, an assessment of the knee pain level and satisfaction, before and after using the herbal knee brace in which the statistics used to analyze the data were frequency, percentage, mean, standard deviation, and hypothesis testing with Dependent and Independent t-test

The results of the study found that after participating in the trial of the herbal knee brace, comparing knee pain in the experiment group before and after participating in the trial, the level of knee pain was reduced in comparison to before using, statistically significant at the 0.05, and reduced in comparison with comparison group, statistically significant at the 0.05. That the satisfaction on the herbal knee brace was found to be at a good level.

Product Development of Applied Herbal Gel Containing a Crude Herbal Extracts from Community Forests to Reduce Muscle Pain

Artit Leeprakhon — 2024-01-02

This study was a quasi-experimental research, with the purpose to study of 1) the physical characteristics of the gel, 2) the important substances in crude extracts used to make gels and 3) the pain reduction results, satisfaction, and side effects after using the gel and tested with a sample of 30 subjects for a period of 3 weeks by using a data recording form to evaluate physical and chemical properties, muscle pain level assessment form and satisfaction assessment form. The data were analyzed using descriptive statistics, frequency distribution and percentages, as well as test differences in muscle pain with paired sample t-test programs. The results of the applied herbal gel found that, the gel has good stability, does not separate layers or precipitate, has a brown color (color chart) and has an average pH of 5.58, which is suitable for the skin. Important substances found in the gel are flavonoids, which have the ability to help reduce inflammation and muscle pain at 45.94 milligrams. The results of effectiveness of using applied herbal gel when tested in sample groups, apply 10 ml. to the affected area and measure the pain level after applying for 30 minutes for 3 weeks. It was found that the average muscle pain before applying the gel in week 1 was 8.00±0.74 and the average muscle pain after applying the gel for the week 3 was 4.50±0.94, which was a statistically significant decrease. In addition, overall satisfaction was at a good level and no side effects. Therefore, it can be concluded that the applied herbal gel containing crude herbal extracts from the community forest did not reveal any side effects in the sample group and was able to reduce muscle pain.

Development of Food Container Forming Machine from Natural Materials

Thanakorn Miengarrom — 2024-01-02

The objectives of this research were to design and develop a food container forming machine and molds for fabricating food containers from natural materials. The food container forming machine was designed to fabricate natural materials by using an electric coil-heated hot press with an electrical operating mechanism control system. The heat transfer efficiency of the container forming machine was studied along with the properties of the natural materials containers, including physical properties, safety assessment, and user satisfaction. There are 5 types of natural materials studied including lotus leaves, banana leaves, spathe of betel nut, bamboo leaves, and water hyacinth leaves. It was found that they all could be used as raw materials for container fabrication. The spathe of betel nut containers showed superior properties for being strong, thick, and capable of containing foods with higher weight compared to other natural materials, with the thickness of 2.24 mm, a density of 0.81 g/cm³, and a permeability percentage of 16%. Safety qualification experiments revealed less than 1 CFU/ml. A consumer acceptance study demonstrated that the spathe of betel nut containers received positive feedback for its general appearance, overall appearance, suitability, color, and texture. In conclusion, using the spathes of betel nut for forming food containers proved to be suitable, biodegradable, and environmentally friendly, as it did not cause pollution to the environment.

Determination of Antioxidant Activity, Flavonoid Compounds and Phenolic Compounds in Herbs

Nunnapus Termwnog — 2024-01-02

The purpose of this study was to determine of antioxidant activity, flavonoid compounds and phenolic compounds of ten herbs in 2%HCl in methanol solvent. The analysis of antioxidant activity was determined by cupric ion reducing antioxidant capacity (CUPRAC), flavonoid compounds were determined by aluminium chloride colorimetry, and phenolic compounds were determined by Folin-Ciocalteau. The result revealed that Bai-ya-nang (Tiliacora triandra) has the highest antioxidant activity and flavonoid compound with 38.0 + 1.7 mg TE/g FW and 882.3 + 20.4 mg QE/g FW, respectively while Cha-om (Acacia pennata) showed the highest phenolic compound with 13364.0 + 671.4 mg GAE /g FW. The results of this research are useful to consumers in selecting herbs for nutritive value and further applying for medicine.