Chemical composition and efficacy of Teak (Tectona grandis L.f.) extracted against Aedes aegypti larvae

Abstract

The objectives of this study were to analyze the chemical composition of teak (Tectona grandis L.f.) extract and to detect the efficacy of teak extract. The mortality rates of Aedes aegypti larva in different concentrations (0.00, 0.25, 0.5, 1, 2.5 and 5% (v/v) at 24 hours were determined. The results revealed that by using Gas Chromatography-Mass Spectrometry (GC-MS), ten chemical compounds of teak extract such as 2,3.-Butanediol (40.35%), 2,3-Butanediol, [R- (R @, R @)] - (38.29%) and aD-Glucopyranoside, methyl (13.89%),etc were identified. Only 6 kinds of chemical composition extracted from teak were tested the efficacy to kill Aedes aegypti larva. The biological assay showed that 3,4,5-trimethoxy- 2.5%, 2,3-Butanediol 5%, 9,10-Anthracenedione, 2-methyl- 0.05. % and 9,10-Anthracenedione, 2-methyl- 0.1% can kill Aedes aegypti larva at 86.00, 91.00, 98.00 and 100.00%, respectively, while 9,10-Anthracenedione, 2-methyl-0.01% and -0.025% can also kill Aedes aegypti larva at rate of 61.00 and 77.00%. This study demonstrated that 9,10-Anthracenedione, 2-methyl- 0.05% and 9,10-Anthracenedione,2- methyl- 0.1% were high potential to develop the appropriated formula for Aedes aegypti larvae control in the further.