Serosurveillance of emerging infectious diseases in Nongbualumpoo Province, 2005

Abstract

The objective of this descriptive study was to confirm the diagnosis of the emerging infectious diseases (EID) in Nongbualumpoo province. Studied population was patients who were diagnosed of EID by using the definition established by the CUPS in the province including Dengue infection, Encephalitis, Leptospirosis, Scrub Typhus and Murine Typhus. The study was conducted during April to September 2005. Blood was drawn from patients fitted with the inclusion criteria by two occasions at 2-weeks interval. One hundred and one patients were recruited in this study. Of these, 91 pair serum were examined. Fifty-two patients were male and 39 were female. Mean age was 17.3 years and 43.4% was in 10-19 years age group. There was no report of encephalitis and Murine Typhus. Laboratory results of these 91 serum pairs revealed that 42.9% was acute primary dengue infection, 4.4% was acute secondary dengue infection, 2.2% was acute primary or secondary dengue infection and 12% was recent secondary dengue infection. 38.5% was non dengue infection. Dengue serotypes 1 and 4 were found in 18 and 1 patients, respectively. One of 8 patients diagnosed of Scrub typhus was confirmed as acute primary dengue infection, the rest was negative for antibody to Scrub typhus. Of the 13 patients diagnosed of Leptospirosis, two were also confirmed as acute primary dengue infection. Dengue surveillance, prevention and control are important strategies to reduce dengue disease burden at present and in the future.